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CS-W001157 4
Total: USD 88.00

2,6-Dichloro-3-iodopyridin-4-amine

  • CAS No. 1235873-11-6

  • Cat. No. CS-0062153
  • Purity≥95%
  • MDL No.MFCD29918898

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloro-3-iodopyridin-4-amine|CS-0062153

Structure of 1235873-11-6

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General Information

  • CAS No. 1235873-11-6
  • Cat. No. CS-0062153
  • Purity ≥95%
  • MDL No. MFCD29918898
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃Cl₂IN₂
  • Molecular Weight None
  • Synonym(s) 4-Pyridinamine,2,6-dichloro-3-iodo-(WS205023)
  • SMILES NC1=C(I)C(Cl)=NC(Cl)=C1

Description

2,6-Dichloro-3-iodopyridin-4-amine serves as a key electrophilic building block in the synthesis of advanced heterocyclic compounds. The iodine substituent enables efficient cross-coupling reactions, while the dichloro pattern enhances reactivity and modulates electronic properties. This bench-stable, moisture-tolerant reagent integrates readily into pharmaceutical and agrochemical development workflows.

Application

2,6-Dichloro-3-iodopyridin-4-amine serves as a versatile building block for constructing substituted pyridine scaffolds in medicinal chemistry and catalytic cross-coupling reactions. The dichloro substitution pattern enables selective functionalization via palladium-catalyzed coupling, while the iodine moiety provides high reactivity in Suzuki, Stille, and Negishi transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for modular synthesis of complex heterocyclic systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.5752
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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