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Structure of 1234616-44-4
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Methyl 3-iodo-1-methyl-1H-indazole-5-carboxylate is a bench-stable, moisture-tolerant building block featuring a strategically positioned iodide for cross-coupling reactions. The electron-deficient indazole core integrates readily into complex heterocyclic architectures, enabling efficient access to bioactive scaffolds in medicinal chemistry and materials science.
Methyl 3-iodo-1-methyl-1H-indazole-5-carboxylate serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The iodide functionality facilitates palladium-catalyzed coupling with boronic acids, stannanes, and other nucleophiles under standard conditions. Its methylated indazole core provides enhanced stability and solubility, while the ester group offers a handle for further derivatization. This compound exhibits excellent bench stability and is compatible with common reaction protocols in medicinal chemistry and process R&D workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: