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CS-W001157 4
Total: USD 88.00

[1,2,4]Triazolo[1,5-a]pyridine-8-carboxylic acid

  • CAS No. 1234616-36-4

  • Cat. No. CS-0053020
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

[1,2,4]Triazolo[1,5-a]pyridine-8-carboxylic acid|CS-0053020

Structure of 1234616-36-4

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General Information

  • CAS No. 1234616-36-4
  • Cat. No. CS-0053020
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight 163.13
  • Synonym(s) None
  • SMILES OC(=O)C1=CC=CN2N=CN=C12

Description

This triazolopyridine carboxylic acid features a rigid, electron-deficient heteroaromatic core that enhances binding affinity in medicinal chemistry applications. The carboxylic acid group enables direct conjugation or salt formation, facilitating integration into bioactive molecules. Bench-stable and moisture-tolerant, it serves as a strategic scaffold for targeted compound libraries.

Application

[1,2,4]Triazolo[1,5-a]pyridine-8-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science, enabling efficient access to fused triazole-pyridine scaffolds. The carboxylic acid functionality facilitates direct derivatization via amide coupling, esterification, or metal-catalyzed cross-coupling reactions. Its high thermal stability and compatibility with diverse functional groups make it suitable for multi-step synthesis and scale-up applications in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   67.49
  • LogP   0.4275
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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