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CS-W001157 4
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Boc-NH-PEG11-NH2

  • CAS No. 1233234-77-9

  • Cat. No. CS-0115519
  • Purity≥97%
  • MDL No.MFCD03453245

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG11-NH2|CS-0115519

Structure of 1233234-77-9

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General Information

  • CAS No. 1233234-77-9
  • Cat. No. CS-0115519
  • Purity ≥97%
  • MDL No. MFCD03453245
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₆₀N₂O₁₃
  • Molecular Weight 644.79
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Description

Boc-NH-PEG11-NH2 features a long, hydrophilic PEG11 spacer flanked by amine functionalities, enabling efficient conjugation and solubility enhancement. The Boc-protected amine ensures stability during storage and handling, while the terminal primary amine facilitates straightforward deprotection and coupling reactions under standard conditions.

Application

Boc-NH-PEG11-NH₂ serves as a versatile, bifunctional linker for conjugation and polymer chemistry. The tert-butyl carbamate (Boc) group provides stable protection of the primary amine, enabling selective deprotection under mild acidic conditions. The 11-atom PEG spacer offers enhanced solubility and reduced aggregation in aqueous environments, while the terminal primary amine facilitates efficient coupling reactions with carboxylic acids, activated esters, or aldehydes. This structure enables precise functionalization in peptide synthesis, bioconjugation, and drug delivery systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   165.88
  • LogP   0.6524
  • H_Acceptors   14
  • H_Donors   2
  • Rotatable_Bonds   35

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