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CS-W001157 4
Total: USD 88.00

3,4-Dimethoxyphenylboronic acid

  • CAS No. 122775-35-3

  • Cat. No. CS-D1792
  • Purity≥95%
  • MDL No.MFCD01074574

*For research and further manufacturing use only, not for direct human use.

3,4-Dimethoxyphenylboronic acid|CS-D1792

Structure of 122775-35-3

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General Information

  • CAS No. 122775-35-3
  • Cat. No. CS-D1792
  • Purity ≥95%
  • MDL No. MFCD01074574
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄
  • Molecular Weight 181.98
  • Synonym(s) None
  • SMILES COC1=CC=C(B(O)O)C=C1OC

Description

3,4-Dimethoxyphenylboronic acid can be used:As a substrate in the cross-coupling reaction with 5,7-dichloropyrido[4,3-d]pyrimidine catalyzed by palladium.As a starting material for the synthesis of buflavine 1, a natural alkaloid.In one of the key synthetic steps for the preparation of lipidated malarial glycosylphosphatidylinositols (GPI) disaccharide.To prepare 3,3,4,4-tetramethoxy-1,1:4,1-terphenyl by reacting with 1,4-dibromobenzene using Pd catalyst.

Synthesis

  • Route1

    References

    • Rosen, Brad M.; Wilson, Daniela A.; Wilson, Christopher J.; Peterca, Mihai; Won, Betty C.; Huang, Chenghong; Lipski, Linda R.; Zeng, Xiangbing; Ungar, Goran; Heiney, Paul A.; Percec, Virgil Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17500 - 17521
  • Route2
    • null|null
      121-43-7
    • In-stock
      4-Bromo-1,2-dimethoxybenzene|CS-W007396
      2859-78-1
    • ~80%
    • In-stock
      3,4-Dimethoxyphenylboronic acid|CS-D1792
      122775-35-3

    References

    • Rosen, Brad M.; Wilson, Daniela A.; Wilson, Christopher J.; Peterca, Mihai; Won, Betty C.; Huang, Chenghong; Lipski, Linda R.; Zeng, Xiangbing; Ungar, Goran; Heiney, Paul A.; Percec, Virgil Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17500 - 17521
  • Route3

    References

    • Pennington, Thomas E.; Kardiman, Cynantya; Hutton, Craig A. Tetrahedron Letters, 2004 , vol. 45, # 35 p. 6657 - 6660

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.6164
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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