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CS-W001157 4
Total: USD 88.00

2,4-Dimethoxyphenylboronic acid

  • CAS No. 133730-34-4

  • Cat. No. CS-D1031
  • Purity≥98%
  • MDL No.MFCD01074590

*For research and further manufacturing use only, not for direct human use.

2,4-Dimethoxyphenylboronic acid|CS-D1031

Structure of 133730-34-4

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General Information

  • CAS No. 133730-34-4
  • Cat. No. CS-D1031
  • Purity ≥98%
  • MDL No. MFCD01074590
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄
  • Molecular Weight 181.98
  • Synonym(s) None
  • SMILES COC1=CC=C(B(O)O)C(OC)=C1

Description

2,4-Dimethoxyphenylboronic acid can be used: As a reactant in meatal-catalyzed SuzukiMiyaura cross-coupling reaction. To prepare hydroxy(trimethoxy)phenanthrene by cross-coupling with bromo(benzyloxy)methoxybenzaldehyde followed by condensation and debenzylation reaction. To synthesize 2,4-dimethoxy-1-(trifluoromethyl)benzene via Cu-catalyzed trifluoromethylation reaction.

Synthesis

  • Route1

    References

    • Laufer, Radoslaw S.; Veith, Ulrich; Taylor, Nicholas J.; Snieckus, Victor Organic Letters, 2000 , vol. 2, # 5 p. 629 - 631
  • Route2
    • null|null
      5419-55-6
    • In-stock
      1-Bromo-2,4-dimethoxybenzene|CS-0008438
      17715-69-4
    • ~%
    • In-stock
      2,4-Dimethoxyphenylboronic acid|CS-D1031
      133730-34-4

    References

    • MEIJI SEIKA PHARMA CO., LTD.; Ohyama, Makoto; Tabata, Yuji; Iida, Maiko; Kaneda, Kaori; Takahata, Sho Patent: US2013/317074 A1, 2013 ; Location in patent: Paragraph 0482; 0483; 0484 ;
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 128, # 22 p. 7176 - 7178

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.6164
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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