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CS-W001157 4
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7-[(Benzyloxy)carbonyl]-7-azaspiro[3.5]nonane-2-carboxylic acid

  • CAS No. 1227610-19-6

  • Cat. No. CS-0050118
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-[(Benzyloxy)carbonyl]-7-azaspiro[3.5]nonane-2-carboxylic acid|CS-0050118

Structure of 1227610-19-6

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General Information

  • CAS No. 1227610-19-6
  • Cat. No. CS-0050118
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₁NO₄
  • Molecular Weight 303.35
  • Synonym(s) 7-Cbz-7-azaspiro[3.5]nonane-2-carboxylic acid
  • SMILES OC(=O)C1CC2(C1)CCN(CC2)C(=O)OCC1=CC=CC=C1

Synthesis

  • Route1
    • Benzyl 2-formyl-7-azaspiro[3.5]nonane-7-carboxylate|CS-0067357
      1227610-18-5
    • ~74%
    • 7-[(Benzyloxy)carbonyl]-7-azaspiro[3.5]nonane-2-carboxylic acid|CS-0050118
      1227610-19-6

    References

    • Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758
  • Route2

    References

    • Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758
  • Route3

    References

    • Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.9
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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