6-Bromo-5-fluoropicolinaldehyde

Name: 6-Bromo-5-fluoropicolinaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1227605-60-8
Cat. No. CS-0442742
Molecule weight204.00
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-5-fluoropicolinaldehyde|CS-0442742

Structure of 1227605-60-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1227605-60-8
Cat. No. CS-0442742
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃BrFNO
Molecular Weight 204.00
Synonym(s) 6-Bromo-5-fluoropyridine-2-carbaldehyde
SMILES C1=CC(=C(Br)N=C1C=O)F

Description

6-Bromo-5-fluoropicolinaldehyde offers a uniquely activated aromatic aldehyde scaffold bearing complementary halogen substituents. This electron-deficient platform enables direct coupling in cross-coupling reactions and serves as a key building block for bioactive heterocycles. The ortho-bromine facilitates palladium-catalyzed transformations, while the para-fluorine enhances reactivity in nucleophilic additions. Bench-stable under standard conditions, it streamlines synthesis of functionalized pharmaceutical intermediates.

Application

6-Bromo-5-fluoropicolinaldehyde serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the aldehyde and halogen sites. Its ortho-halogenated pyridine scaffold facilitates palladium-catalyzed cross-coupling reactions and provides enhanced metabolic stability. The aldehyde group offers ready access to imines, oximes, and hydrazones, while the fluorine and bromine substituents enable strategic derivatization for target-focused synthesis. Bench-stable and compatible with standard purification methods, it functions efficiently in multi-step synthetic sequences.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.96
LogP 1.7957
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

6-Bromo-5-fluoropicolinaldehyde sigma6-Bromo-5-fluoropicolinaldehyde manufacturer6-Bromo-5-fluoropicolinaldehyde price6-Bromo-5-fluoropicolinaldehyde structure6-Bromo-5-fluoropicolinaldehyde SDSbuy 6-Bromo-5-fluoropicolinaldehyde6-Bromo-5-fluoropicolinaldehyde supplier6-Bromo-5-fluoropicolinaldehyde uses6-Bromo-5-fluoropicolinaldehyde molecular weightprice of 6-Bromo-5-fluoropicolinaldehyde6-Bromo-5-fluoropicolinaldehyde chemical name formula of 6-Bromo-5-fluoropicolinaldehyde

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Bromo-5-fluoropicolinaldehyde

CAS No. 1227605-60-8

Recommended Products