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Structure of 1227575-06-5
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Methyl 2-chloro-3-(trifluoromethyl)isonicotinate features a trifluoromethyl group that enhances electron-withdrawing character, while the chloro substituent provides a reactive handle for nucleophilic substitution. This bench-stable ester integrates readily into heterocyclic synthesis, offering high compatibility in cross-coupling and functionalization workflows under standard conditions.
Methyl 2-chloro-3-(trifluoromethyl)isonicotinate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds. The molecule combines a reactive chloro group at the 2-position with a strongly electron-withdrawing trifluoromethyl substituent at the 3-position, enhancing electrophilicity and facilitating nucleophilic substitution or metal-catalyzed coupling reactions. Its bench-stable nature and straightforward purification make it ideal for multi-step synthesis workflows targeting bioactive heterocycles.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: