1-[3,6-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-pyridinyl]ethanone

Name: 1-[3,6-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-pyridinyl]ethanone
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1227068-67-8
Cat. No. CS-W019712
Purity≥97%
MDL No.MFCD18427628

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-[3,6-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-pyridinyl]ethanone|CS-W019712

Structure of 1227068-67-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This pyridine-based boronate ester integrates a stable tetramethyl-1,3,2-dioxaborolane moiety with a ketone-functionalized side chain, enabling direct coupling in Suzuki-Miyaura reactions. The electron-deficient pyridine ring enhances reactivity, while the bench-stable boronate resists hydrolysis under standard conditions.

Application

1-[3,6-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-pyridinyl]ethanone serves as a versatile boron-containing building block for Suzuki-Miyaura coupling reactions. The pyridine core enables integration into bioactive scaffolds, while the pinacol boronate group offers excellent stability, ease of handling, and compatibility with diverse functional groups. This reagent facilitates efficient C–C bond formation under mild conditions, making it well-suited for late-stage functionalization in medicinal chemistry and process development workflows.

General Information

CAS No. 1227068-67-8
Cat. No. CS-W019712
Purity ≥97%
MDL No. MFCD18427628
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₂₂BNO₃
Molecular Weight 251.13
Synonym(s) 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl]ethanone; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinyl]ethanone
SMILES CC(N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1)=O

Computational Chemistry Data

TPSA 38.77
LogP 1.7964
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

1227068-67-8 sigma1227068-67-8 manufacturer1227068-67-8 price1227068-67-8 structure1227068-67-8 SDSbuy 1227068-67-81227068-67-8 supplier1227068-67-8 uses1227068-67-8 molecular weightprice of 1227068-67-81227068-67-8 chemical name formula of 1227068-67-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-[3,6-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-pyridinyl]ethanone

CAS No. 1227068-67-8

Recommended Products