(R)-2-Amino-3-hydroxypropanamide hydrochloride

Name: (R)-2-Amino-3-hydroxypropanamide hydrochloride
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CAS No. 122702-20-9
Cat. No. CS-0158516
Purity≥95%
MDL No.MFCD00050702

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Amino-3-hydroxypropanamide hydrochloride|CS-0158516

Structure of 122702-20-9

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General Information

CAS No. 122702-20-9
Cat. No. CS-0158516
Purity ≥95%
MDL No. MFCD00050702
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₉ClN₂O₂
Molecular Weight 140.57
Synonym(s) D-Serinamide Hydrochloride(WX665005)
SMILES O=C(N)[C@H](N)CO.[H]Cl

Description

(R)-2-Amino-3-hydroxypropanamide hydrochloride features a chiral α-amino acid scaffold with a hydroxyl group at the β-position, enabling precise stereochemical control in peptide synthesis. This bench-stable derivative integrates readily into peptidomimetic architectures and serves as a key building block for bioactive molecules requiring defined spatial orientation and hydrogen-bonding capacity.

Application

(R)-2-Amino-3-hydroxypropanamide hydrochloride serves as a key chiral building block for synthesizing β-hydroxy amino acids and related pharmacophores. Its well-defined stereochemistry enables reliable incorporation into peptidomimetics and kinase inhibitor scaffolds. The compound exhibits good bench stability, facilitates straightforward purification via crystallization, and demonstrates compatibility with standard amine protection and coupling protocols in solid-phase synthesis.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 89.34
LogP -1.7869
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Amide

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-Amino-3-hydroxypropanamide hydrochloride

CAS No. 122702-20-9

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