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Structure of 122453-98-9
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This pyrrole derivative features a 4-chlorophenyl substituent at the 4-position, enhancing electron-withdrawing character and facilitating downstream functionalization. The carboxylic acid group enables direct coupling reactions and serves as a key handle for conjugation in bioconjugate and pharmaceutical applications.
4-(4-Chlorophenyl)-1H-pyrrole-3-carboxylic acid serves as a versatile building block for bioactive heterocycles, enabling direct incorporation into pharmaceutical scaffolds via standard amide coupling and decarboxylation protocols. The ortho-carboxylic acid functionality facilitates conjugation with amines, while the 4-chlorophenyl group provides enhanced metabolic stability and π–π stacking potential in target binding. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses of kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: