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3-Chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

  • CAS No. 1220219-73-7

  • Cat. No. CS-0109938
  • Molecule weight257.50
  • Purity≥98%
  • MDL No.MFCD16995268

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine|CS-0109938

Structure of 1220219-73-7

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General Information

  • CAS No. 1220219-73-7
  • Cat. No. CS-0109938
  • Purity ≥98%
  • MDL No. MFCD16995268
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄BClFNO₂
  • Molecular Weight 257.50
  • Synonym(s) 3-Chloro-2-fluoropyridne-5-boronic acid pinacol ester
  • SMILES CC1(C)C(C)(C)OB(C2=CN=C(F)C(Cl)=C2)O1

Synthesis

  • Route1

    References

    • PFIZER LIMITED; BELL, Andrew Simon; DE GROOT, Marcel John; LEWTHWAITE, Russell Andrew; MARSH, Ian Roger; SCIAMMETTA, Nunzio; STORER, Robert Ian; SWAIN, Nigel Alan Patent: WO2012/95781 A1, 2012 ; Location in patent: Page/Page column 102 ; WO 2012/095781 A1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   31.35
  • LogP   2.1733
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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