Lot numbers can be found on the outside label of a product:
1,3-Bis(4-chlorophenyl)urea
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CAS No. 1219-99-4
- Cat. No. CS-0182191
- Purity≥97%
- MDL No.MFCD00018541
*For research and further manufacturing use only, not for direct human use.
Structure of 1219-99-4
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General Information
- CAS No. 1219-99-4
- Cat. No. CS-0182191
- Purity ≥97%
- MDL No. MFCD00018541
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₃H₁₀Cl₂N₂O
- Molecular Weight 281.14
- Synonym(s) 4,4-Dichlorocarbanilide
- SMILES O=C(NC1=CC=C(C=C1)Cl)NC2=CC=C(C=C2)Cl
Description
Sodium thioglycolate is commonly used in microbiology as a reducing agent in microbial culture media to facilitate the growth of anaerobic organisms. It helps to maintain anaerobic conditions by reducing oxygen and creating an environment suitable for the growth of microbes that require low oxygen levels. Sodium thioglycolate also has bacteriostatic properties that inhibit the growth of certain bacterial species, which can be useful in selective and differential media formulations. It is commonly used in media for the enrichment, isolation, and identification of Clostridium spp., Salmonella spp., and other anaerobic bacteria in environmental samples. When used in microbial media, sodium thioglycolate is normally added at a concentration of 0.05%-0.5% (w/v).Sodium thioglycolate has several microbial applications due to its reducing and bacteriostatic properties. It is commonly used as an ingredient in many microbial culture media for the growth and identification of anaerobic bacteria from various environmental, food, and beverage samples.
Application
1,3-Bis(4-chlorophenyl)urea serves as a stable, bench-ready building block for urea-based pharmacophores and functional materials. Its ortho-substituted aryl groups confer enhanced metabolic stability and π-π stacking potential, while the central urea moiety enables hydrogen bonding and compatibility with standard coupling protocols. Functions effectively in solid-phase synthesis and solution-phase derivatization, facilitating access to diverse heterocyclic scaffolds and bioactive analogs.
Synthesis
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Route1
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201230-82-2 -
106-47-8
- ~91%
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In-stock
1219-99-4
References
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Giannoccaro, Potenzo Journal of Organometallic Chemistry, 1987 , vol. 336, p. 271 - 278
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References
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Sergeev; Artamkina; Beletskaya Russian Journal of Organic Chemistry, 2003 , vol. 39, # 12 p. 1741 - 1752
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References
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Nandakumar, Mecheril V. Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1989 - 1990
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Quality Control
Computational Chemistry Data
- TPSA 41.13
- LogP 4.6374
- H_Acceptors 1
- H_Donors 2
- Rotatable_Bonds 2
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Key Words
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