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(R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate hydrochloride

  • CAS No. 1217858-20-2

  • Cat. No. CS-0041691
  • Purity≥95%
  • MDL No.MFCD11101388

*For research and further manufacturing use only, not for direct human use.

(R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate hydrochloride|CS-0041691

Structure of 1217858-20-2

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General Information

  • CAS No. 1217858-20-2
  • Cat. No. CS-0041691
  • Purity ≥95%
  • MDL No. MFCD11101388
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁ClN₂O₂
  • Molecular Weight 236.74
  • Synonym(s) tert-butyl N-[(3R)-pyrrolidin-3-ylmethyl]carbamate hydrochloride
  • SMILES O=C(OC(C)(C)C)NC[C@H]1CNCC1.[H]Cl

Description

(R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate hydrochloride features a chiral pyrrolidinomethyl scaffold with a bench-stable carbamate protecting group, enabling straightforward incorporation into peptide-based syntheses. The hydrochloride salt enhances solubility in polar solvents while maintaining stability under standard handling conditions.

Application

(R)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate hydrochloride serves as a chiral building block for the synthesis of pyrrolidine-containing scaffolds in medicinal chemistry. The protected amine enables selective functionalization and orthogonal deprotection under mild conditions. Its bench-stable crystalline form facilitates handling and purification, while the (R)-stereogenic center ensures stereochemical fidelity in target molecule construction.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.5424
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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