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CS-W001157 4
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8-Aminoquinoline-4-carboxylic acid

  • CAS No. 121689-23-4

  • Cat. No. CS-0196586
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-Aminoquinoline-4-carboxylic acid|CS-0196586

Structure of 121689-23-4

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General Information

  • CAS No. 121689-23-4
  • Cat. No. CS-0196586
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈N₂O₂
  • Molecular Weight 188.18
  • Synonym(s) 4-Quinolinecarboxylicacid,8-amino-(9CI)
  • SMILES C1=CC2=C(C(=C1)N)N=CC=C2C(=O)O

Description

8-Aminoquinoline-4-carboxylic acid features a fused quinoline core with strategically positioned amino and carboxylic acid groups, enabling dual functionality in coordination chemistry and molecular scaffolding. This electron-rich heterocycle integrates readily into bioactive architectures and facilitates metal chelation through its nitrogen-donor framework, offering utility in catalyst design and medicinal chemistry applications.

Application

8-Aminoquinoline-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of quinoline-based scaffolds with enhanced solubility and hydrogen-bonding capacity. Its dual functional groups—amine and carboxylic acid—facilitate diverse conjugations, including amide bond formation and metal coordination, while maintaining bench stability and ease of purification. This compound functions effectively in peptide coupling and heterocyclic derivatization workflows, supporting downstream synthesis of bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   76.21
  • LogP   1.5152
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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