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1-(Pyridin-2-yl)cyclopropanamine dihydrochloride

  • CAS No. 1215107-39-3

  • Cat. No. CS-0044500
  • Molecule weight207.10
  • Purity≥97%
  • MDL No.MFCD09028134

*For research and further manufacturing use only, not for direct human use.

1-(Pyridin-2-yl)cyclopropanamine dihydrochloride|CS-0044500

Structure of 1215107-39-3

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General Information

  • CAS No. 1215107-39-3
  • Cat. No. CS-0044500
  • Purity ≥97%
  • MDL No. MFCD09028134
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂Cl₂N₂
  • Molecular Weight 207.10
  • Synonym(s) 1-(2-Pyridyl)cyclopropylamine Dihydrochloride
  • SMILES NC1(C2=NC=CC=C2)CC1.[H]Cl.[H]Cl

Description

1-(Pyridin-2-yl)cyclopropanamine dihydrochloride features a rigid cyclopropyl ring fused to a pyridine moiety, delivering enhanced conformational control. The amine functionality, delivered as a stable dihydrochloride salt, ensures excellent solubility and handling under standard conditions. This scaffold integrates readily into medicinal chemistry libraries, offering a bioisosteric alternative to linear alkylamines with improved metabolic stability.

Application

1-(Pyridin-2-yl)cyclopropanamine dihydrochloride serves as a stable, bench-ready building block for medicinal chemistry and catalytic synthesis. The cyclopropyl amine functionality enables direct incorporation into bioactive scaffolds, while the pyridine moiety offers orthogonal reactivity for metal coordination and hydrogen bonding in drug discovery applications. Its dihydrochloride salt form enhances solubility and purification efficiency in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.873
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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