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Structure of 1214328-84-3
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Methyl 5-bromo-3-(trifluoromethyl)picolinate features a trifluoromethyl group at the 3-position and a bromo substituent at the 5-position of the picolinate ring, enabling selective cross-coupling reactions. The ester functionality supports derivatization, while the electron-withdrawing trifluoromethyl moiety enhances reactivity in transition-metal-catalyzed transformations. This compound serves as a key building block for bioactive heterocycles and pharmaceutical intermediates under standard conditions.
Methyl 5-bromo-3-(trifluoromethyl)picolinate serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromo group enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl and ester functionalities offer enhanced metabolic stability and tunable polarity. This compound exhibits excellent bench stability and facilitates efficient functionalization in late-stage diversification strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: