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(S)-2-Amino-2-(3-methoxyphenyl)ethan-1-ol

  • CAS No. 1213016-49-9

  • Cat. No. CS-0037658
  • Molecule weight167.21
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-2-(3-methoxyphenyl)ethan-1-ol|CS-0037658

Structure of 1213016-49-9

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General Information

  • CAS No. 1213016-49-9
  • Cat. No. CS-0037658
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₂
  • Molecular Weight 167.21
  • Synonym(s) (S)-2-Amino-3-(2-methoxyphenyl)ethanol
  • SMILES COC1=CC([C@H](N)CO)=CC=C1

Description

(S)-2-Amino-2-(3-methoxyphenyl)ethan-1-ol is a chiral building block featuring a primary amine and hydroxyl group flanking a stereogenic center. This configuration enables selective incorporation into bioactive molecules, particularly in the synthesis of pharmaceutical intermediates requiring precise stereochemical control. The methoxy-substituted aromatic ring enhances solubility and modulates electronic properties.

Application

(S)-2-Amino-2-(3-methoxyphenyl)ethan-1-ol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive compounds through established amine and alcohol functional group transformations. Its bench-stable structure facilitates straightforward purification and compatibility with diverse coupling and protection strategies, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.48
  • LogP   0.6873
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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