Val-Ala-PAB

Name: Val-Ala-PAB
Brand: ChemScene
Availability: InStock
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CAS No. 1343476-44-7
Cat. No. CS-0103274
Purity≥97%
MDL No.MFCD32641649

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 1343476-44-7
Cat. No. CS-0103274
Purity ≥97%
MDL No. MFCD32641649
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₃N₃O₃
Molecular Weight None
Synonym(s) None
SMILES CC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O

Description

Val-Ala-PAB features a sterically hindered valyl-alanyl dipeptide scaffold coupled with a photolabile para-azidobenzoyl (PAB) group, enabling precise spatiotemporal control in bioconjugation workflows. This stable, bench-ready derivative facilitates efficient caging and release of bioactive molecules under UV irradiation.

Application

Val-Ala-PAB serves as a versatile dipeptide building block for peptide synthesis, featuring the valine-alanine sequence with a para-aminobenzoyl (PAB) terminus. The PAB group enhances solubility and provides a robust handle for conjugation or fluorescent tagging. Its stability under standard coupling conditions and compatibility with common protecting groups make it ideal for constructing complex peptide architectures and bioconjugates in medicinal chemistry workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 104.45
LogP 0.6054
H_Acceptors 4
H_Donors 4
Rotatable_Bonds 6

Other Classifications

Life Science ADC Related Compound ADC Linker

Building Blocks Functional Group Amine

Building Blocks Functional Group Amide

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

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Val-Ala-PAB

CAS No. 1343476-44-7

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