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CS-W001157 4
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4-(N-Methylaminocarbonyl)phenylboronic acid

  • CAS No. 121177-82-0

  • Cat. No. CS-W022019
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD03788427

*For research and further manufacturing use only, not for direct human use.

4-(N-Methylaminocarbonyl)phenylboronic acid|CS-W022019

Structure of 121177-82-0

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General Information

  • CAS No. 121177-82-0
  • Cat. No. CS-W022019
  • Purity ≥98%
  • MDL No. MFCD03788427
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BNO₃
  • Molecular Weight None
  • Synonym(s) 4-(N-Methylaminocarbonyl)Benzeneboronic Acid
  • SMILES C1=CC(=CC=C1B(O)O)C(=O)NC

Description

4-(N-Methylaminocarbonyl)phenylboronic acid features a boronic acid group conjugated to a para-substituted phenyl ring bearing an N-methylcarbamoyl handle. This electron-deficient arylboronic acid integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, offering enhanced stability and compatibility with diverse functional groups in synthetic workflows.

Application

4-(N-Methylaminocarbonyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The N-methylcarbamoyl group enhances solubility and stability while maintaining compatibility with diverse functional groups. Its bench-stable nature and straightforward purification make it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.56
  • LogP   -1.274
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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