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CS-W001157 4
Total: USD 88.00

4-Bromo-5-fluoro-2-methylpyridine

  • CAS No. 1211590-24-7

  • Cat. No. CS-W018573
  • Purity≥97%
  • MDL No.MFCD18251020

*For research and further manufacturing use only, not for direct human use.

4-Bromo-5-fluoro-2-methylpyridine|CS-W018573

Structure of 1211590-24-7

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General Information

  • CAS No. 1211590-24-7
  • Cat. No. CS-W018573
  • Purity ≥97%
  • MDL No. MFCD18251020
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrFN
  • Molecular Weight 190.01
  • Synonym(s) 4-Bromo-2-methyl-5-fluoropyridine
  • SMILES CC1=NC=C(F)C(Br)=C1

Description

4-Bromo-5-fluoro-2-methylpyridine features a sterically accessible pyridine core with complementary halogen and methyl substituents, enabling selective cross-coupling and functionalization in late-stage diversification. This bench-stable heterocycle integrates readily into pharmaceutical intermediates and agrochemical scaffolds.

Application

4-Bromo-5-fluoro-2-methylpyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its compatible halogen substituents. The fluorine and methyl groups provide orthogonal reactivity and electronic modulation, enhancing target molecule diversity. Its bench-stable nature and straightforward purification facilitate integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.29162
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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