tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate

Name: tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1211586-09-2
Cat. No. CS-B1364
Purity≥97%
MDL No.MFCD15071432

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate|CS-B1364

Structure of 1211586-09-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1211586-09-2
Cat. No. CS-B1364
Purity ≥97%
MDL No. MFCD15071432
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₂₀N₂O₂
Molecular Weight 212.29
Synonym(s) None
SMILES O=C(OC(C)(C)C)N1CC2(C1)CC(N)C2

Description

tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate features a rigid spirocyclic scaffold with a primary amine and ester handle, enabling direct incorporation into complex nitrogen-containing frameworks. The tert-butyl group enhances stability and simplifies purification, while the azaspirocore provides conformational restraint ideal for medicinal chemistry applications.

Application

tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry applications, enabling efficient access to nitrogen-containing heterocycles. The protected amine and carboxylate groups offer orthogonal reactivity, facilitating sequential functionalization. Its bench-stable nature and compatibility with standard coupling and reduction protocols make it ideal for modular synthesis of complex bioactive molecules.

Synthesis

Route1
- 1239589-54-8
- ~95%
- In-stock
  
  1211586-09-2
References
- Radchenko, Dmytro S.; Pavlenko, Sergiy O.; Grygorenko, Oleksandr O.; Volochnyuk, Dmitriy M.; Shishkina, Svitlana V.; Shishkin, Oleg V.; Komarov, Igor V. Journal of Organic Chemistry, 2010 , vol. 75, # 17 p. 5941 - 5952

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 55.56
LogP 1.3446
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Amine

Building Blocks Skeleton Aliphatic heterocycle compounds Azetidine compounds

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Key Words

1211586-09-2 sigma1211586-09-2 manufacturer1211586-09-2 price1211586-09-2 structure1211586-09-2 SDSbuy 1211586-09-21211586-09-2 supplier1211586-09-2 uses1211586-09-2 molecular weightprice of 1211586-09-21211586-09-2 chemical name formula of 1211586-09-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate

CAS No. 1211586-09-2

Recommended Products