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Structure of 1211538-62-3
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Methyl 3-bromo-6-(trifluoromethyl)picolinate features a brominated pyridine core with a trifluoromethyl group at the 6-position and a methyl ester at C-3. This electron-deficient heterocycle enables efficient cross-coupling reactions, particularly in Pd-catalyzed transformations. The trifluoromethyl moiety enhances metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. Its bench-stable nature supports straightforward handling under standard conditions.
Methyl 3-bromo-6-(trifluoromethyl)picolinate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established bromo functionality. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the ester moiety allows for further derivatization. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: