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Structure of 1211533-09-3
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5-Cyanopyrazine-2-carboxylic acid features a fused pyrazine core bearing complementary electron-withdrawing groups: a nitrile at the 5-position and a carboxylic acid at the 2-position. This arrangement imparts strong acidity and enhanced electrophilicity, enabling direct incorporation into heterocyclic scaffolds via coupling reactions. The molecule exhibits stability under standard bench conditions and demonstrates favorable solubility in polar aprotic solvents, facilitating use in synthetic transformations and materials development.
5-Cyanopyrazine-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrazine-based scaffolds through standard functional group transformations. Its dual functionality—cyano and carboxylic acid groups—supports diverse coupling reactions, including amidation and esterification, with excellent bench stability and straightforward purification. Widely employed in medicinal chemistry and agrochemical research, it functions as a key intermediate in the construction of bioactive molecules and API precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: