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Structure of 1211526-51-0
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5-Bromo-2-methyl-3-(trifluoromethyl)pyridine features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability. The bromine substituent enables facile palladium-catalyzed cross-coupling, while the methyl group provides steric control. This combination facilitates efficient integration into complex heterocyclic scaffolds under standard conditions.
5-Bromo-2-methyl-3-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry and catalytic cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the bromo and methyl substituents enable selective functionalization via Pd-catalyzed couplings. The compound exhibits good bench stability and facilitates efficient access to substituted pyridine scaffolds common in agrochemicals and pharmaceuticals.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: