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Structure of 1211523-68-0
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5-(Difluoromethyl)-2-pyridinamine integrates a difluoromethyl group at the 5-position of a pyridinamine scaffold, delivering enhanced metabolic stability and improved lipophilicity. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling efficient incorporation into bioactive molecules through direct functionalization or coupling reactions under mild conditions.
5-(Difluoromethyl)-2-pyridinamine serves as a versatile building block in medicinal chemistry, enabling direct incorporation of a difluoromethyl group into bioactive scaffolds. Its pyridinamine functionality facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions, while the difluoromethyl moiety enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: