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Structure of 1211518-35-2
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Methyl 6-chloro-5-(trifluoromethyl)picolinate features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the chloro substituent provides a reactive handle for cross-coupling. This bench-stable ester integrates readily into synthetic routes requiring electron-deficient heterocycles, enabling efficient access to advanced intermediates in medicinal chemistry and agrochemical development.
Methyl 6-chloro-5-(trifluoromethyl)picolinate serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the methyl ester facilitates downstream derivatization. The molecule exhibits excellent bench stability and is compatible with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: