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CS-W001157 4
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6-Bromo-3-methylpyridine-2-carboxylic acid

  • CAS No. 1211516-18-5

  • Cat. No. CS-0050272
  • Purity≥97%
  • MDL No.MFCD16249865

*For research and further manufacturing use only, not for direct human use.

6-Bromo-3-methylpyridine-2-carboxylic acid|CS-0050272

Structure of 1211516-18-5

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General Information

  • CAS No. 1211516-18-5
  • Cat. No. CS-0050272
  • Purity ≥97%
  • MDL No. MFCD16249865
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₂
  • Molecular Weight 216.03
  • Synonym(s) None
  • SMILES CC1=C(N=C(Br)C=C1)C(O)=O

Description

6-Bromo-3-methylpyridine-2-carboxylic acid features a pyridine core functionalized with bromo, methyl, and carboxylic acid groups at strategic positions. This configuration enables direct incorporation into diverse synthetic scaffolds, particularly in medicinal chemistry and agrochemical development. The compound exhibits enhanced reactivity in cross-coupling and derivatization reactions due to the electron-withdrawing carboxylate and halogen moieties.

Application

6-Bromo-3-methylpyridine-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the pyridine core. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, while the carboxylic acid and methyl functionalities offer orthogonal handles for derivatization. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for medicinal chemistry campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.85072
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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