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CS-W001157 4
Total: USD 88.00

Cycloocta-1,5-diene;dichloropalladium

  • CAS No. 12107-56-1

  • Cat. No. CS-0035163
  • Purity≥98%
  • MDL No.MFCD00012412

*For research and further manufacturing use only, not for direct human use.

Cycloocta-1,5-diene;dichloropalladium|CS-0035163

Structure of 12107-56-1

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General Information

  • CAS No. 12107-56-1
  • Cat. No. CS-0035163
  • Purity ≥98%
  • MDL No. MFCD00012412
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂Cl₂Pd
  • Molecular Weight 285.49
  • Synonym(s) dichloro[(1,2,5,6-η)-cycloocta-1,5-diene]palladium; Dichloro[(1,2,5,6-η)-cycloocta-1,5-diene]palladium
  • SMILES Cl[Pd](C)(C)Cl.C1/C=C\CC/C=C\C1

Description

Dichloro(1,5-cyclooctadiene)palladium(II) is a commonly used catalyst to protect alcohols as acetals by treating with 2-benzyloxy-1-propene; to synthesize bicyclooctanes from diethyl malonate and in alkene carbonylation. It can also be used to catalyze the Heck coupling of nonactivated vinyl phosphates with electron deficient alkenes; the synthesis of benzo[b]thiophenes from thioenols and to prepare an active catalyst for Mizoroki-Heck and Suzuki-Miyaura cross-coupling reactions.

Application

Cycloocta-1,5-diene;dichloropalladium serves as a stable, bench-ready precatalyst for palladium-catalyzed cross-coupling reactions. Its well-defined coordination sphere enables efficient formation of active Pd(0) species under mild conditions, facilitating Suzuki, Stille, and Negishi couplings with broad functional group tolerance. The ligand-stabilized structure enhances catalyst longevity and reproducibility in synthetic workflows.

Synthesis

  • Route1
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      46059-16-9
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      5259-72-3
    • ~98%
    • In-stock
      Cycloocta-1,5-diene;dichloropalladium|CS-0035163
      12107-56-1

    References

    • Rettig,M.F.; Wing,R.M.; Wiger,G.R. Journal of the American Chemical Society, 1981 , vol. 103, p. 2980
  • Route2
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      31741-66-9
    • ~%
    • In-stock
      Cycloocta-1,5-diene;dichloropalladium|CS-0035163
      12107-56-1

    References

    • Rettig,M.F.; Wing,R.M.; Wiger,G.R. Journal of the American Chemical Society, 1981 , vol. 103, p. 2980
  • Route3
    • null|null
      26764-39-6
    • null|null
      5259-72-3
    • ~%
    • In-stock
      Cycloocta-1,5-diene;dichloropalladium|CS-0035163
      12107-56-1

    References

    • Journal of the American Chemical Society, , vol. 103, p. 2980

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.2169
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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