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CS-W001157 4
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4-Bromo-3-methoxypyridine hydrochloride

  • CAS No. 1209335-53-4

  • Cat. No. CS-0031482
  • Purity≥97%
  • MDL No.MFCD11226828

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-methoxypyridine hydrochloride|CS-0031482

Structure of 1209335-53-4

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General Information

  • CAS No. 1209335-53-4
  • Cat. No. CS-0031482
  • Purity ≥97%
  • MDL No. MFCD11226828
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrClNO
  • Molecular Weight 224.48
  • Synonym(s) Pyridine, 4-broMo-3-Methoxy-, hydrochloride
  • SMILES COC1=C(C=CN=C1)Br.[H]Cl

Description

4-Bromo-3-methoxypyridine hydrochloride delivers a brominated pyridine scaffold with a methoxy group at the 3-position, enabling direct functionalization in cross-coupling and electrophilic substitution reactions. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating handling in synthetic workflows.

Application

4-Bromo-3-methoxypyridine hydrochloride serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromo group enables palladium-catalyzed cross-coupling reactions, while the methoxy substituent provides regioselective functionalization potential. As a stable crystalline salt, it offers ease of handling, purification, and storage—ideal for use in Suzuki, Stille, or Buchwald-Hartwig transformations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.2745
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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