6-Bromo-8-chloroimidazo[1,2-a]pyrazine

Name: 6-Bromo-8-chloroimidazo[1,2-a]pyrazine
Brand: ChemScene
Availability: InStock
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CAS No. 1208083-37-7
Cat. No. CS-W022466
Purity≥97%
MDL No.MFCD11846485

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-8-chloroimidazo[1,2-a]pyrazine|CS-W022466

Structure of 1208083-37-7

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General Information

CAS No. 1208083-37-7
Cat. No. CS-W022466
Purity ≥97%
MDL No. MFCD11846485
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃BrClN₃
Molecular Weight None
Synonym(s) None
SMILES BrC2=C[N]1C(=NC=C1)C(=N2)Cl

Description

6-Bromo-8-chloroimidazo[1,2-a]pyrazine is a halogenated heterocyclic scaffold featuring complementary electrophilic sites at the 6- and 8-positions. This electron-deficient core enables selective cross-coupling reactions and serves as a key building block in medicinal chemistry. The molecule exhibits enhanced stability under standard bench conditions and facilitates efficient incorporation into complex molecular architectures.

Application

6-Bromo-8-chloroimidazo[1,2-a]pyrazine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its dual halogen substituents enable palladium-catalyzed cross-coupling reactions with broad functional group tolerance. The scaffold exhibits excellent bench stability and facilitates the construction of complex imidazopyrazine-based pharmacophores through sequential derivatization.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 30.19
LogP 2.1452
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Key Words

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6-Bromo-8-chloroimidazo[1,2-a]pyrazine

CAS No. 1208083-37-7

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