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CS-W001157 4
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6-(Piperidin-1-yl)pyridine-3-carboxylic acid

  • CAS No. 120800-50-2

  • Cat. No. CS-0127012
  • Purity≥97%
  • MDL No.MFCD03791231

*For research and further manufacturing use only, not for direct human use.

6-(Piperidin-1-yl)pyridine-3-carboxylic acid|CS-0127012

Structure of 120800-50-2

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General Information

  • CAS No. 120800-50-2
  • Cat. No. CS-0127012
  • Purity ≥97%
  • MDL No. MFCD03791231
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂O₂
  • Molecular Weight 206.24
  • Synonym(s) 6-Piperidinonicotinic acid
  • SMILES O=C(C1=CC=C(N2CCCCC2)N=C1)O

Description

6-(Piperidin-1-yl)pyridine-3-carboxylic acid features a pyridine core functionalized with a piperidinyl group at the 6-position and a carboxylic acid at the 3-position, enabling strong coordination in metal complexes. This arrangement enhances solubility and facilitates integration into bioactive scaffolds for pharmaceutical development.

Application

6-(Piperidin-1-yl)pyridine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and derivatization protocols. Its pyridine core provides strong hydrogen-bonding capacity and favorable pharmacokinetic properties, while the piperidinyl group enhances solubility and modulates basicity. The carboxylic acid functionality facilitates direct conjugation or further functionalization, making it well-suited for lead optimization campaigns and scaffold diversity generation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   53.43
  • LogP   1.7701
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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