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CS-W001157 4
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Benzyl 3-amino-4,4-difluoropiperidine-1-carboxylate

  • CAS No. 1207852-56-9

  • Cat. No. CS-0168729
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Benzyl 3-amino-4,4-difluoropiperidine-1-carboxylate|CS-0168729

Structure of 1207852-56-9

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General Information

  • CAS No. 1207852-56-9
  • Cat. No. CS-0168729
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆F₂N₂O₂
  • Molecular Weight 270.28
  • Synonym(s) 1-Piperidinecarboxylic acid, 3-amino-4,4-difluoro-, phenylmethyl ester
  • SMILES O=C(N1CC(N)C(F)(F)CC1)OCC2=CC=CC=C2

Synthesis

  • Route1
    • Benzyl 3-((tert-butoxycarbonyl)amino)-4,4-difluoropiperidine-1-carboxylate|CS-0449140
      1052713-44-6
    • ~%
    • Benzyl 3-amino-4,4-difluoropiperidine-1-carboxylate|CS-0168729
      1207852-56-9

    References

    • PFIZER INC.; NINKOVIC, Sacha; BRAGANZA, John Frederick; COLLINS, Michael Raymond; KATH, John Charles; LI, Hui; RICHTER, Daniel Tyler Patent: WO2010/16005 A1, 2010 ; Location in patent: Page/Page column 95; 97-98 ; WO 2010/016005 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.9915
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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