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CS-W001157 4
Total: USD 88.00

(4-Ethoxy-2-methoxyphenyl)boronic acid

  • CAS No. 1207443-48-8

  • Cat. No. CS-0101374
  • Purity≥96%
  • MDL No.MFCD04037217

*For research and further manufacturing use only, not for direct human use.

(4-Ethoxy-2-methoxyphenyl)boronic acid|CS-0101374

Structure of 1207443-48-8

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General Information

  • CAS No. 1207443-48-8
  • Cat. No. CS-0101374
  • Purity ≥96%
  • MDL No. MFCD04037217
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃BO₄
  • Molecular Weight 196.01
  • Synonym(s) 4-ETHOXY-2-METHOXYPHENYLBORONIC ACID
  • SMILES COC1=CC(OCC)=CC=C1B(O)O

Description

This boronic acid features a strategically positioned ethoxy and methoxy group that enhance solubility and stability under standard conditions. The electron-donating substituents improve reactivity in Suzuki-Miyaura coupling, enabling efficient C–C bond formation with aryl halides.

Application

(4-Ethoxy-2-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-methoxy and para-ethoxy substituents enhance solubility and modulate electronic properties, while the boronic acid group offers reliable stability and compatibility with diverse functional groups. Its bench-stable nature and straightforward purification facilitate integration into multi-step synthetic sequences for pharmaceutical and agrochemical applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.2263
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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