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CS-W001157 4
Total: USD 88.00

5-(Methoxycarbonyl)pyrazine-2-carboxylic acid

  • CAS No. 1206250-26-1

  • Cat. No. CS-0225479
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(Methoxycarbonyl)pyrazine-2-carboxylic acid|CS-0225479

Structure of 1206250-26-1

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General Information

  • CAS No. 1206250-26-1
  • Cat. No. CS-0225479
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O₄
  • Molecular Weight 182.13
  • Synonym(s) None
  • SMILES O=C(C1=NC=C(C(OC)=O)N=C1)O

Description

This pyrazine-based diacid scaffold integrates a methoxycarbonyl group at the 5-position and a carboxylic acid at the 2-position, enabling direct coupling or derivatization in synthetic routes. The electron-deficient heterocyclic core enhances reactivity in nucleophilic substitution and metal-catalyzed transformations, while the orthogonal functional groups support modular assembly in pharmaceutical and materials chemistry applications.

Application

5-(Methoxycarbonyl)pyrazine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its dual carboxylic acid and ester functionalities enable straightforward derivatization via amidation, esterification, or Suzuki coupling. The molecule exhibits good bench stability and facilitates purification by recrystallization or chromatography, making it well-suited for scalable synthesis of pyrazine-based pharmaceuticals and functional polymers.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   89.38
  • LogP   -0.0386
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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