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(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride

  • CAS No. 1204818-19-8

  • Cat. No. CS-0158432
  • Purity≥97%
  • MDL No.MFCD06659146

*For research and further manufacturing use only, not for direct human use.

(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride|CS-0158432

Structure of 1204818-19-8

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General Information

  • CAS No. 1204818-19-8
  • Cat. No. CS-0158432
  • Purity ≥97%
  • MDL No. MFCD06659146
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁ClF₃NO₂
  • Molecular Weight 269.65
  • Synonym(s) Sitagliptin-2
  • SMILES C(C1=CC(=C(C=C1F)F)F)[C@H](CC(=O)O)N.Cl

Synthesis

  • Route1
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      1374966-98-9
    • ~%
    • In-stock
      (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride|CS-0158432
      1204818-19-8

    References

    • Drug Process Licensing Associates, LLC Patent: US2012/123144 A1, 2012 ; Location in patent: Page/Page column 4-5 ;
  • Route2

    References

    • Jiangsu Hengrui Medicine Co., Ltd. Patent: US2011/130587 A1, 2011 ; Location in patent: Page/Page column 5 ;
  • Route3

    References

    • Tasnadi, Gabor; Forro, Enik; Fueloep, Ferenc Organic and Biomolecular Chemistry, 2010 , vol. 8, # 4 p. 793 - 799

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.8702
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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