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CS-W001157 4
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N1-Methylcyclohexane-1,4-diamine

  • CAS No. 38362-02-6

  • Cat. No. CS-0151020
  • Purity≥96%
  • MDL No.MFCD14583097

*For research and further manufacturing use only, not for direct human use.

N1-Methylcyclohexane-1,4-diamine|CS-0151020

Structure of 38362-02-6

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General Information

  • CAS No. 38362-02-6
  • Cat. No. CS-0151020
  • Purity ≥96%
  • MDL No. MFCD14583097
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆N₂
  • Molecular Weight 128.22
  • Synonym(s) N-Methyl-cyclohexane-1,4-diamine
  • SMILES CNC1CCC(CC1)N

Description

N1-Methylcyclohexane-1,4-diamine features a rigid cyclohexane scaffold with strategically positioned primary and tertiary amine groups, enabling effective coordination in catalytic systems. This bench-stable derivative offers enhanced solubility in organic media while maintaining strong nucleophilicity, making it valuable for ligand design and synthetic intermediates.

Application

N1-Methylcyclohexane-1,4-diamine serves as a versatile bifunctional building block in medicinal chemistry and catalysis. Its pendant amine functionality enables straightforward derivatization, while the cyclohexane scaffold provides conformational rigidity and metabolic stability. The compound exhibits excellent bench stability, facilitates efficient purification via standard chromatography or salt formation, and functions effectively in amide coupling, reductive amination, and heterocycle synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.4757
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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