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Structure of 1203681-52-0
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tert-Butyl 3-(4-bromophenyl)azetidine-1-carboxylate features a rigid azetidine core linked to a para-brominated phenyl group, enabling efficient coupling in transition metal-catalyzed reactions. The tert-butyl carbamate handle ensures stability and convenient deprotection under mild acidic conditions. This bench-stable reagent integrates readily into medicinal chemistry campaigns targeting bioactive heterocycles.
tert-Butyl 3-(4-bromophenyl)azetidine-1-carboxylate serves as a versatile building block for the synthesis of bioactive azetidine-containing compounds. The bromophenyl group enables facile Suzuki-Miyaura and other Pd-catalyzed couplings, while the tert-butyl carbamate protects the nitrogen under standard conditions. This stability facilitates purification and handling, making it ideal for iterative synthesis in medicinal chemistry and API development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: