(R)-3-Methoxypyrrolidine

Name: (R)-3-Methoxypyrrolidine
Brand: ChemScene
Availability: InStock
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CAS No. 120099-60-7
Cat. No. CS-0053757
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 120099-60-7

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Description

(R)-3-Methoxypyrrolidine is a chiral pyrrolidine derivative featuring a methoxy group at the 3-position, offering enhanced solubility and stability compared to unsubstituted analogs. This configuration provides stereochemical precision for applications in asymmetric synthesis, medicinal chemistry, and ligand design. The molecule integrates readily into complex scaffolds under standard conditions.

Application

(R)-3-Methoxypyrrolidine serves as a versatile chiral building block in medicinal chemistry, enabling stereoselective synthesis of bioactive molecules. Its pyrrolidine core provides a rigid, nitrogen-containing heterocyclic scaffold with favorable pharmacokinetic properties. The methoxy group at the 3-position offers enhanced solubility and metabolic stability, while the (R)-configuration ensures predictable stereochemical outcomes in coupling reactions. This compound exhibits excellent bench stability, facilitates efficient purification, and demonstrates broad functional group tolerance in standard synthetic transformations, making it ideal for API development and high-throughput screening campaigns.

General Information

CAS No. 120099-60-7
Cat. No. CS-0053757
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁NO
Molecular Weight 101.15
Synonym(s) None
SMILES CO[C@H]1CNCC1

Computational Chemistry Data

TPSA 21.26
LogP -0.0053
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02,GHS07
Signal Word : Danger	UN#: 1993
Class : 3	Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-3-Methoxypyrrolidine

CAS No. 120099-60-7

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