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CS-W001157 4
Total: USD 88.00

Thalline

  • CAS No. 120-15-0

  • Cat. No. CS-W000806
  • Purity≥98%
  • MDL No.MFCD00090494

*For research and further manufacturing use only, not for direct human use.

Thalline|CS-W000806

Structure of 120-15-0

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General Information

  • CAS No. 120-15-0
  • Cat. No. CS-W000806
  • Purity ≥98%
  • MDL No. MFCD00090494
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO
  • Molecular Weight 163.22
  • Synonym(s) Thallin
  • SMILES COC1=CC(CCCN2)=C2C=C1

Description

Thalline delivers a robust, bench-stable scaffold for constructing complex heterocycles and functionalized aromatic systems. This electron-rich platform integrates seamlessly into cross-coupling workflows, enabling rapid access to diverse molecular architectures under standard conditions.

Application

Thalline serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of complex heterocyclic frameworks and functionalized scaffolds. Its stable, bench-ready nature facilitates straightforward handling and purification, while its predictable reactivity under standard conditions supports broad functional group tolerance. Widely employed in medicinal chemistry and process development, Thalline functions as a key intermediate for C–C and C–heteroatom bond formation, offering reliable performance across diverse synthetic transformations.

Synthesis

  • Route1

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1933 - 1939
  • Route2
    • N-allyl-4-methoxyaniline|CS-0368176
      71954-46-6
    • ~31%
    • In-stock
      Thalline|CS-W000806
      120-15-0

    References

    • Chemical Communications, , vol. 48, # 47 p. 5877 - 5879
  • Route3
    • null|null
      88342-91-0
    • ~%
    • In-stock
      Thalline|CS-W000806
      120-15-0
    • null|null
      88343-24-2

    References

    • Chemical and Pharmaceutical Bulletin, , vol. 31, # 7 p. 2220 - 2233

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   2.0533
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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