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Structure of 1198408-35-3
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tert-Butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate features a pyridine nitrogen positioned ortho to the piperidine tether, enabling direct functionalization. The tert-butyl carbamate group provides stability and ease of removal under mild acidic conditions. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
tert-Butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate serves as a versatile building block for constructing pyridine-containing heterocycles in medicinal chemistry. The tert-butyl carbamate group provides excellent bench stability and ease of removal under mild acidic conditions, while the primary amine enables direct derivatization via acylation, alkylation, or coupling reactions. Its piperidine scaffold offers favorable conformational properties and functional group tolerance, facilitating integration into diverse API candidates through standard synthetic protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: