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Structure of 1198-30-7
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1-Isoquinolinecarbonitrile features a nitrile group fused to the isoquinoline core, delivering high electron deficiency and enhanced reactivity in transition metal-catalyzed coupling reactions. This rigid, planar structure facilitates efficient π-stacking and enables direct incorporation into advanced heterocyclic architectures under mild conditions.
1-Isoquinolinecarbonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to isoquinoline-based scaffolds through nucleophilic addition and metal-catalyzed coupling reactions. Its nitrile group exhibits high bench stability and tolerates a range of functional groups, facilitating downstream transformations such as amidation, reduction, or cyclization. The molecule functions effectively in Pd- and Ni-catalyzed cross-coupling protocols, supporting the construction of complex pharmaceutical intermediates with predictable reactivity profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: