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Structure of 406933-21-9
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3-(Trifluoromethyl)picolinonitrile features a trifluoromethyl group flanking a nitrile-substituted pyridine ring, delivering enhanced electron-withdrawing character and improved metabolic stability. This configuration enables efficient incorporation into bioactive scaffolds and facilitates transition-metal-catalyzed coupling reactions under standard conditions.
3-(Trifluoromethyl)picolinonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocycles via nucleophilic addition and cyclization reactions. Its dual electron-withdrawing groups—trifluoromethyl and nitrile—enhance reactivity in conjugate additions and facilitate downstream transformations. The molecule exhibits excellent bench stability and is compatible with common purification methods, making it ideal for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: