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N-Benzylprop-2-yn-1-amine

  • CAS No. 1197-51-9

  • Cat. No. CS-0047035
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Benzylprop-2-yn-1-amine|CS-0047035

Structure of 1197-51-9

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General Information

  • CAS No. 1197-51-9
  • Cat. No. CS-0047035
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁N
  • Molecular Weight 145.20
  • Synonym(s) BENZYL-PROP-2-YNYL-AMINE
  • SMILES C#CCNCC1=CC=CC=C1

Description

N-Benzylprop-2-yn-1-amine features a propargylamine scaffold with a benzyl substituent, delivering a robust platform for click chemistry and bioconjugation. The terminal alkyne enables efficient copper-catalyzed azide-alkyne cycloaddition, while the benzylic nitrogen enhances solubility and stability under standard conditions. This compound serves as a key building block in probe development and molecular tagging applications.

Synthesis

  • Route1
    • null|null
      106-96-7
    • null|null
      100-46-9
    • ~83%
    • In-stock
      N-Benzylprop-2-yn-1-amine|CS-0047035
      1197-51-9

    References

    • Iafe, Robert G.; Kuo, Jonathan L.; Hochstatter, Dustin G.; Saga, Tomomi; Turner, Jonathan W.; Merlic, Craig A. Organic Letters, 2013 , vol. 15, # 3 p. 582 - 585
  • Route2
    • null|null
      121508-78-9
    • ~75%
    • In-stock
      N-Benzylprop-2-yn-1-amine|CS-0047035
      1197-51-9

    References

    • Jia, Zhao; Wei, Shen; Zhu, Qing Biological and Pharmaceutical Bulletin, 2010 , vol. 33, # 4 p. 725 - 728
  • Route3
    • null|null
      624-65-7
    • null|null
      100-46-9
    • ~52%
    • In-stock
      N-Benzylprop-2-yn-1-amine|CS-0047035
      1197-51-9

    References

    • Sipkina; Balova Russian Journal of General Chemistry, 2003 , vol. 73, # 12 p. 1893 - 1899

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.4094
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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