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Structure of 1196156-66-7
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Methyl 3-ethynylpyridine-2-carboxylate features a pyridine ring bearing both a methyl ester and a terminal alkyne group at adjacent positions, enabling direct incorporation into click chemistry and transition-metal-catalyzed coupling reactions. The electron-deficient pyridine core enhances reactivity in nucleophilic substitution processes, while the ethynyl functionality offers robust handle for Sonogashira and Huisgen-type transformations. This compound exhibits excellent stability under standard bench conditions and facilitates rapid assembly of complex heterocyclic architectures in synthetic and medicinal chemistry workflows.
Methyl 3-ethynylpyridine-2-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized pyridine derivatives via CuAAC and Sonogashira coupling reactions. The conjugated alkyne and ester functionalities exhibit excellent bench stability and tolerate a range of reaction conditions, facilitating downstream transformations including heterocycle construction and late-stage diversification in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: