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Structure of 1196155-24-4
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5-Ethynyl-2-(trifluoromethyl)pyridine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the terminal alkyne enables efficient copper-catalyzed coupling reactions. This combination supports rapid assembly of complex heterocycles in medicinal chemistry and materials science applications.
5-Ethynyl-2-(trifluoromethyl)pyridine serves as a versatile building block for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling efficient access to triazole-linked scaffolds. The ethynyl group exhibits high reactivity under standard conditions, while the trifluoromethyl and pyridine functionalities provide enhanced metabolic stability and tunable polarity. This compound offers excellent bench stability, simplifies purification, and functions effectively in both small-molecule library synthesis and macrocyclic scaffold construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: