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CS-W001157 4
Total: USD 88.00

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

  • CAS No. 1195995-72-2

  • Cat. No. CS-0020016
  • Purity≥95%
  • MDL No.MFCD09607735

*For research and further manufacturing use only, not for direct human use.

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine|CS-0020016

Structure of 1195995-72-2

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General Information

  • CAS No. 1195995-72-2
  • Cat. No. CS-0020016
  • Purity ≥95%
  • MDL No. MFCD09607735
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇BN₂O₂
  • Molecular Weight 220.08
  • Synonym(s) 2-Amino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • SMILES NC1=NC=CC(B2OC(C)(C)C(C)(C)O2)=C1

Application

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyridin-2-amine moiety enables direct incorporation into biaryl scaffolds and heterocyclic frameworks, while the pinacol boronate group offers excellent bench stability, functional group tolerance, and ease of purification. This reagent facilitates efficient C–C bond formation under mild conditions, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H319
Precautionary Statements : P264-P270-P280-P330-P405-P501

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Computational Chemistry Data

  • TPSA   57.37
  • LogP   0.963
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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