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Structure of 1194032-23-9
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This pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and two geminal fluorines at the 4-position, conferring enhanced metabolic stability and conformational rigidity. The methyl group at C2 further modulates steric environment, enabling precise control in peptidomimetic design. Ideal for building constrained bioactive scaffolds in medicinal chemistry applications.
(2S)-1-[(tert-Butoxy)carbonyl]-4,4-difluoro-2-methylpyrrolidine-2-carboxylic acid serves as a versatile chiral building block for the synthesis of fluorinated pyrrolidine scaffolds. The difluoro substitution enhances metabolic stability and modulates conformational rigidity, while the Boc group enables straightforward deprotection under mild acidic conditions. Its stability, compatibility with standard coupling reagents, and suitability for peptide and heterocycle synthesis make it ideal for medicinal chemistry applications requiring fluorinated aliphatic motifs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: