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CS-W001157 4
Total: USD 88.00

tert-Butyl hept-6-yn-1-ylcarbamate

  • CAS No. 1192373-48-0

  • Cat. No. CS-0375949
  • Purity≥95%
  • MDL No.MFCD24467680

*For research and further manufacturing use only, not for direct human use.

tert-Butyl hept-6-yn-1-ylcarbamate|CS-0375949

Structure of 1192373-48-0

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General Information

  • CAS No. 1192373-48-0
  • Cat. No. CS-0375949
  • Purity ≥95%
  • MDL No. MFCD24467680
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₂
  • Molecular Weight 211.31
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCCCC#C

Description

tert-Butyl hept-6-yn-1-ylcarbamate features a terminal alkyne group flanked by a robust tert-butyl carbamate protecting group, enabling stable storage and selective deprotection. This bifunctional scaffold integrates seamlessly into copper-catalyzed click chemistry workflows and supports efficient conjugation in peptide synthesis and bioconjugation applications.

Application

tert-Butyl hept-6-yn-1-ylcarbamate serves as a versatile, bench-stable building block for the synthesis of alkyne-containing scaffolds. Its terminal alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the tert-butoxycarbonyl (Boc) group provides orthogonal protection for primary amines. The molecule exhibits excellent functional group tolerance and facilitates straightforward purification, making it well-suited for iterative peptide and heterocyclic compound assembly in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   2.7047
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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